Quantitative evaluation of the infrapatellar fat pad in knee osteoarthritis: MRI-based radiomic signature.

ABSTRACT:

Background

The infrapatellar fat pad (IFP) may have bilateral influence on knee osteoarthritis (KOA). IFP evaluation may be a key contributor to the diagnostic and clinical management of KOA. Few studies have evaluated KOA-related IFP alteration with radiomics. We investigated radiomic signature for the assessment of IFP for KOA progression in older adults.

Methods

A total of 164 knees were enrolled and grouped based on Kellgren-Lawrence (KL) scoring. MRI-based radiomic features were calculated from IFP segmentation. The radiomic signature was developed using the most predictive subset of features and the machine-learning algorithm with minimum relative standard deviation. KOA severity and structure abnormality were assessed using a modified whole-organ magnetic resonance im

SUBMITTER: Ye Q 

PROVIDER: S-EPMC10127010 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature