In-hospital antibiotic use for severe chronic obstructive pulmonary disease exacerbations: a retrospective observational study.

ABSTRACT:

Background

The use of antibiotics in mild to severe acute exacerbations of chronic obstructive pulmonary disease (COPD) remains controversial.

Aim

To explore in-hospital antibiotic use in severe acute exacerbations of COPD (AECOPD), to analyze determinants of in-hospital antibiotic use, and to investigate its association with hospital length of stay (LOS) and in-hospital mortality.

Methods

A retrospective, observational study was conducted in Ghent University Hospital. Severe AECOPD were defined as hospitalizations for AECOPD (ICD-10 J44.0 and J44.1) discharged between 2016 and 2021. Patients with a concomitant diagnosis of pneumonia or 'pure' asthma were excluded. An alluvial plot was used to describe antibiotic treatment patterns. Logistic regression analyses identi

SUBMITTER: Vanoverschelde A 

PROVIDER: S-EPMC10127022 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature