Alcohol use, dementia risk, and sex: a systematic review and assessment of alcohol-attributable dementia cases in Europe.

ABSTRACT:

Background

High-risk alcohol use is an established modifiable risk factor for dementia. However, prior reviews have not addressed sex differences in alcohol-related dementia risk. In this systematic review, we take a sex-specific perspective towards the alcohol-dementia link, taking into account the age of dementia onset.

Methods

We searched electronic databases for original cohort or case-control studies investigating the association between alcohol use and dementia. Two restrictions were considered: First, studies had to report results stratified by sex. Second, given the fact that the age at dementia onset seems to affect the alcohol-dementia link, studies were required to distinguish between early-onset and late-onset dementia (cut-off: 65 years). Additionally, the contr

SUBMITTER: Kilian C 

PROVIDER: S-EPMC10127029 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature