Environmental chamber studies of eye and respiratory irritation from use of a peracetic acid-based hospital surface disinfectant.

ABSTRACT:

Objective

To characterize personal exposures and measures of eye and respiratory tract irritation in controlled environmental chamber studies of 44 healthy adult volunteers simulating upper-bound use of peracetic acid (PAA)-based surface disinfectant for terminal cleaning of hospital patient rooms.

Design

Experimental, within-subject, double-blinded cross-over design.

Methods

Objective and subjective exposure effects were assessed for PAA and its components: acetic acid (AA) and hydrogen peroxide (HP). Deionized water was included as a control. Breathing-zone concentrations of PAA, AA, and HP were assessed for 8 female multiday volunteers (5 consecutive days) and 36 single-day volunteers (32 females and 4 males). Wetted cloths were used to wipe high-touch surfaces for

SUBMITTER: Dalton PH 

PROVIDER: S-EPMC10127244 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature