Comparison of different reference values for lung function: implications of inconsistent use among centers.

ABSTRACT:

Background

For interpretation of pulmonary function tests (PFTs), reference values based on sex, age, height and ethnicity are needed. In Norway, the European Coal and Steel Community (ECSC) reference values remain widely used, in spite of recommendations to implement the more recent Global Lung Function Initiative (GLI) reference values.

Objective

To assess the effects of changing from ECSC to GLI reference values for spirometry, DLCO and static lung volumes, using a clinical cohort of adults with a broad range in age and lung function.

Methods

PFTs from 577 adults (18-85 years, 45% females) included in recent clinical studies were used to compare ECSC and GLI reference values for FVC, FEV1, DLCO, TLC and RV. Percent predicted and lower limit of normal (LLN) were cal

SUBMITTER: Mangseth H 

PROVIDER: S-EPMC10127329 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature