Principles and Reporting of Bayesian Trials.

ABSTRACT: Bayesian clinical trials are becoming popular owing to their adaptive, flexible, and versatile nature. Such trials typically require specification of the prior distribution and construction of the likelihood function; subsequently, inference is made on the basis of the posterior distribution. In comparison with frequentist trial designs, there are less established guidelines on how to report Bayesian trials. We provide a general overview on key components of the design, conduct, and analysis of Bayesian trials and elaborate on the reporting guidelines dos and don'ts.

SUBMITTER: Lee JJ 

PROVIDER: S-EPMC10127518 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature