Pesticide exposure and incident thyroid cancer among male pesticide applicators in agricultural health study.

ABSTRACT:

Background

Many pesticides are known to have thyroid-disrupting properties. However, few studies have evaluated the association between specific pesticide ingredients and risk of thyroid cancer. We investigated self-reported pesticide use and incident thyroid cancer in the Agricultural Health Study (AHS), a large cohort of occupationally-exposed male pesticide applicators.

Methods

The AHS is a prospective cohort of licensed pesticide applicators in Iowa and North Carolina. At enrollment (1993-1997) and follow-up (1999-2005), participants reported use of 50 pesticides. We characterized exposure as ever use (44 pesticides with ≥5 exposed cases) and by cumulative intensity-weighted lifetime days (22 pesticides with ≥10 exposed cases), a metric that accounts for factors that inf

SUBMITTER: Lerro CC 

PROVIDER: S-EPMC10127519 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature