Use of geriatric assessment in cancer clinical trials: A systematic review.

ABSTRACT:

Background

Older adults are underrepresented in cancer clinical trials despite accounting for most of the disease burden. Geriatric assessment (GA) could be used in clinical trials of cancer drugs for older adults to improve the clinical evidence for cancer drug use among older adults.

Objective

To examine patterns of use of GA in cancer clinical trials.

Methods

We undertook a systematic review of the studies reporting use of GA in a clinical trial setting for all cancer types and published between January 2010 and January 2020. Characteristics of GA use were extracted for each study, along with study phase, cancer type, and participant age (PROSPERO: CRD42020170584).

Results

We identified 320 studies and 63 studies met the final inclusion criteria. Among 74 pu

SUBMITTER: Lee W 

PROVIDER: S-EPMC10129289 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature