A task-general connectivity model reveals variation in convergence of cortical inputs to functional regions of the cerebellum.

ABSTRACT: While resting-state fMRI studies have provided a broad picture of the connectivity between human neocortex and cerebellum, the degree of convergence of cortical inputs onto cerebellar circuits remains unknown. Does each cerebellar region receive input from a single cortical area or convergent inputs from multiple cortical areas? Here, we use task-based fMRI data to build a range of cortico-cerebellar connectivity models, each allowing for a different degree of convergence. We compared these models by their ability to predict cerebellar activity patterns for novel Task Sets. Models that allow some degree of convergence provided the best predictions, arguing for convergence of multiple cortical inputs onto single cerebellar voxels. Importantly, the degree of convergence varied across the cer

SUBMITTER: King M 

PROVIDER: S-EPMC10129326 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature