Project description:The article by Nygaard and others (2016) proposes that applying batch correction approaches to microarray data from studies with unbalanced designs may inadvertently exaggerate the differences observed. In seeking to illustrate their point, Nygaard and others (2016) utilized a dataset (GSE61901) from a study we published (Towfic and others, 2014) and showed that one analysis pipeline utilizing the traditional approach to batch correction (ComBat) yielded over 1000 differentially expressed probesets, while an alternative approach proposed by Nygaard and others (2016). (utilizing batch as a fixed effect and averaging technical replicates) recovered 11 differentially expressed probesets.

| S-EPMC5379915 | biostudies-literature

Response to Letter to the Editor by Goupell et al.

Project description: Not available

| S-EPMC11073616 | biostudies-literature

Reply to Letter to the Editor.

Project description: Not available

| S-EPMC5628931 | biostudies-literature

Response to letter to editor: 'Comment on Arch et al., Trials. 2016;17:517'.

Project description:In October 2015 we published the paper 'Measurement of HbA1c in multicentre diabetes trials - should blood samples be tested locally or sent to a central laboratory: an agreement analysis'. Chatterjee and Pradhan have submitted a letter to the editor asking critical questions regarding the methods we used. We offer this letter in response.Trial registrationEudract No. 2010-023792-25. Registered on 4 November 2010. ISRCTN No. ISRCTN29255275 . Registered on 12 November 2010.

| S-EPMC5446760 | biostudies-literature

Feng et al 2019 - Microarray Raw Data

Project description:In order to identify mechanisms of drug resistance to HER2-targeted therapy, we performed cDNA microarray analysis on drug naiive BT474 and drug resistant BT474 cells treated with lapatinib for 0, 10, and 20 hrs.

2020-04-14 | GSE136304 | GEO

More details are needed about the use of multicenter propensity score matching analysis.

Project description: Not available

| S-EPMC10129896 | biostudies-literature

Blood glucose levels and COVID-19. Reply to Sardu C, D'Onofrio N, Balestrieri ML et al [letter] and Lepper PM, Bals R, Juni P et al [letter].

Project description: Not available

| S-EPMC7438680 | biostudies-literature

Hemani et al. reply.

Project description: Not available

| S-EPMC4404158 | biostudies-literature

Response to van Dyck, O'Dell, & Mecca letter to the editor regarding Andrews et al. (2019).

Project description: Not available