Baseline brain imaging signs in patients with ischaemic stroke by the presence of atrial fibrillation: the ENCHANTED trial.

ABSTRACT:

Background

We aimed to assess the association of atrial fibrillation (AF) on outcomes in a post hoc analysis of the ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) and how this association is modified by baseline imaging features.

Methods

Inverse probability of treatment weight was used to remove baseline imbalances between those with and without AF. The primary outcome was the modified Rankin Scale (mRS) scores at 90 days. Secondary outcomes were symptomatic intracerebral haemorrhage (sICH), early neurological deterioration or death within 24 h, and death at 90 days. The logistic regression model was used to determine the associations.

Results

Of the 3285 patients included in this analysis, 636 (19%) had AF at baseline. Compared with non-AF

SUBMITTER: Wang X 

PROVIDER: S-EPMC10130001 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature