Correlation between gene mutation status and clinicopathologic features in early multiple primary lung cancer.

ABSTRACT:

Objective

To understand the characteristics of genetic mutation in multiple primary lung cancer so as to guide clinical decisions in targeted therapy.

Methods

We analyzed a total of 265 tumors from 111 patients who underwent surgery for multiple lung cancers. Individual tumors were subjected to histological evaluation and gene mutation analysis using ABI 7500 Fluorescence quantitative PCR.

Results

In this study, we analyzed demographic and clinical parameters such as age, gender, smoking, alcohol consumption, pathological type, number of nodules, and other details of 111 patients with early multiple primary lung cancer. We also compared the clinicopathologic characteristics of different populations based on the gene mutation status of pulmonary nodules. Subsequently,

SUBMITTER: Teng F 

PROVIDER: S-EPMC10130385 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature