The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study.

ABSTRACT:

Background

Autonomic dysfunction, including gastrointestinal, cardiovascular, and urinary dysfunction, is often present in early Parkinson's Disease (PD). However, the knowledge of the longitudinal progression of these symptoms, and the connection between different autonomic domains, is limited. Furthermore, the relationship between the presence of autonomic symptoms in early-stage PD and olfactory dysfunction, a possible marker of central nervous system involvement, has not been fully investigated.

Objectives

We aimed to investigate the occurrence and progression of autonomic dysfunction in recently diagnosed (< 2 years) untreated PD patients and determine any coexistence of symptoms in individual patients. We also investigated the relationship between autonomic symptoms, o

SUBMITTER: Stewart CB 

PROVIDER: S-EPMC10130433 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature