Surgical outcomes of gallbladder cancer: the OMEGA retrospective, multicentre, international cohort study.

ABSTRACT:

Background

Gallbladder cancer (GBC) is rare but aggressive. The extent of surgical intervention for different GBC stages is non-uniform, ranging from cholecystectomy alone to extended resections including major hepatectomy, resection of adjacent organs and routine extrahepatic bile duct resection (EBDR). Robust evidence here is lacking, however, and survival benefit poorly defined. This study assesses factors associated with recurrence-free survival (RFS), overall survival (OS) and morbidity and mortality following GBC surgery in high income countries (HIC) and low and middle income countries (LMIC).

Methods

The multicentre, retrospective Operative Management of Gallbladder Cancer (OMEGA) cohort study included all patients who underwent GBC resection across 133 centres betwe

SUBMITTER: Balakrishnan A 

PROVIDER: S-EPMC10130604 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature