Chemotherapy and targeted therapy for advanced biliary tract cancers: an umbrella review.

ABSTRACT:

Background

Malignant tumors of the biliary system are characterized by a high degree of malignancy and strong invasiveness, and they are usually diagnosed at late stages with poor prognosis. For patients with advanced biliary tract cancer, chemotherapy and targeted therapy are two of the options available to improve prognosis and delay tumor progression. This study aimed to comprehensively evaluate the safety and effectiveness of various chemotherapy schemes for the treatment of advanced biliary tract cancer in published systematic reviews and meta-analyses (SRoMAs).

Methods

An umbrella review method was adopted, which aims to summarize the existing evidence from multiple studies around a research topic. SRoMAs up to April 9, 2022, were identified using PubMed, Web of Scienc

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10131316 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature