Awake prone position in COVID-19-related acute respiratory failure: a meta-analysis of randomized controlled trials.

ABSTRACT:

Background

We aimed to investigate the effects of awake prone positioning (APP) in nonintubated adult patients with acute hypoxemic respiratory failure due to COVID-19.

Methods

The PubMed, Embase, Web of Science and Cochrane Central Register databases were searched up to June 1, 2022. All randomized trials investigating the effects of APP were included in the present meta-analysis. The primary outcome was intubation rate, and the secondary outcomes included the length of intensive care unit (ICU) stay, hospital stay, and mortality. Prescribed subgroup analysis was also conducted.

Results

A total of 10 randomized trials enrolling 2324 patients were ultimately included in the present study. The results indicated that APP was associated with a significant reduction in th

SUBMITTER: Qin S 

PROVIDER: S-EPMC10131466 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature