Maternal iron status in early pregnancy and childhood body fat measures and cardiometabolic risk factors: A population-based prospective cohort.

ABSTRACT:

Background

Whether maternal iron status during pregnancy is associated with cardiometabolic health in the offspring is poorly known.

Objectives

We aimed to assess the associations of maternal iron status during early pregnancy with body fat measures and cardiometabolic risk factors in children aged 10 y.

Methods

In a population-based cohort study among 3718 mother-child pairs, we measured ferritin, transferrin, and transferrin saturation during early pregnancy. We obtained child BMI, fat mass index, and android/gynoid fat mass ratio by DXA, subcutaneous fat index, visceral fat index, pericardial fat index, and liver fat fraction by magnetic resonance imaging and assessed systolic and diastolic blood pressure, serum lipids, glucose, insulin, and CRP at 10 y.

Results

SUBMITTER: Quezada-Pinedo HG 

PROVIDER: S-EPMC10131616 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature