Advanced Soft Robotic System for In Situ 3D Bioprinting and Endoscopic Surgery.

ABSTRACT: Three-dimensional (3D) bioprinting technology offers great potential in the treatment of tissue and organ damage. Conventional approaches generally rely on a large form factor desktop bioprinter to create in vitro 3D living constructs before introducing them into the patient's body, which poses several drawbacks such as surface mismatches, structure damage, and high contamination along with tissue injury due to transport and large open-field surgery. In situ bioprinting inside a living body is a potentially transformational solution as the body serves as an excellent bioreactor. This work introduces a multifunctional and flexible in situ 3D bioprinter (F3DB), which features a high degree of freedom soft printing head integrated into a flexible robotic arm to deliver multilayered biomateria

SUBMITTER: Thai MT 

PROVIDER: S-EPMC10131836 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature