The association of apolipoprotein B with chronic kidney disease in the Chinese population.

ABSTRACT:

Background

Whether serum apolipoprotein B (ApoB) is a risk factor for the development of Chronic kidney disease (CKD) has not been fully established in the general population. Therefore, our study evaluated the correlation between serum ApoB level and CKD to look for an alternative approach for CKD prevention and treatment in the general population.

Methods

There were 146,533 participants in this cross-sectional study. 3,325 participants with more than 2 measurements were enrolled in the retrospective longitudinal study with at least a 3-year follow-up. ApoB was measured by the immunoturbidimetric method in 6 centers. Our study defined CKD as an estimated glomerular filtration rate (eGFR) < 90 mL/min/1.73 m². The Spearman rank correlation analysis and the Random F

SUBMITTER: Xu Y 

PROVIDER: S-EPMC10132458 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature