A mathematical model of vascular and hemodynamics changes in early and late forms of preeclampsia.

ABSTRACT: Preeclampsia-eclampsia syndrome is a leading cause of maternal mortality. The precise etiology of preeclampsia is still not well-defined and different forms exist, including early and late forms or preeclampsia, which may arise via distinctly different mechanisms. Low-dose aspirin administered at the end of the first trimester in women identified as high risk has been shown to reduce the incidence of early, but not late, preeclampsia; however, current risk factors show only fair predictive capability. There is a pressing need to develop accurate descriptions for the different forms of preeclampsia. This paper presents 1D fluid, solid, growth, and remodeling models for pregnancies complicated with early and late forms of preeclampsia. Simulations affirm a broad set of literature results tha

SUBMITTER: Sedaghati F 

PROVIDER: S-EPMC10132946 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature