Impact of Bacteria Types on the Clinical Outcomes of Spontaneous Bacterial Peritonitis.

ABSTRACT:

Background and aims

Cirrhotic patients presenting with spontaneous bacterial peritonitis (SBP) have elevated risk of short-term mortality. While high Model for End-Stage Liver Disease-Sodium score (MELD-Na) and ascites culture yielding multi-drug resistance (MDR) bacteria are well established risk factors for further aggravating mortality, the impact of individual, causative microorganisms and their respective pathogenesis have not been previously investigated.

Methods

This is a retrospective study of 267 cirrhotic patients at two tertiary care hospitals undergoing paracentesis from January 2015 to January 2021 who presented with ascitic PMN count > 250 cells^/mm³. The primary outcome was SBP progression defined as death or liver transplantation within 1

SUBMITTER: Furey C 

PROVIDER: S-EPMC10133085 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature