A qualitative study exploring the consumer experience of receiving self-initiated polygenic risk scores from a third-party website.

ABSTRACT: The number of people accessing their own polygenic risk scores (PRSs) online is rapidly increasing, yet little is known about why people are doing this, how they react to the information, and what they do with it. We conducted a qualitative interview-based study with people who pursued PRSs through Impute.me, to explore their motivations for seeking PRS information, their emotional reactions, and actions taken in response to their results. Using interpretive description, we developed a theoretical model describing the experience of receiving PRSs in a direct-to-consumer (DTC) context. Dissatisfaction with healthcare was an important motivator for seeking PRS information. Participants described having medical concerns dismissed and experiencing medical distrust, which drove them to self-adv

SUBMITTER: Lowes K 

PROVIDER: S-EPMC10133316 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature