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The efficacy of thoracoscopic surgery for descending necrotizing mediastinitis.


ABSTRACT:

Objectives

Thoracotomy is a reliable approach for descending necrotizing mediastinitis (DNM), and the use of video-assisted thoracic surgery (VATS), a minimally invasive procedure, has been increasing. However, which approach is more effective for DNM treatment is controversial.

Methods

We analysed patients who underwent mediastinal drainage via VATS or thoracotomy, using a database with DNM from 2012 to 2016 in Japan, which was constructed by the Japanese Association for Chest Surgery and the Japan Broncho-esophagological Society. The primary outcome was 90-day mortality, and the adjusted risk difference between the VATS and thoracotomy groups using a regression model, which incorporated the propensity score, was estimated.

Results

VATS was performed on 83 patients and thoracotomy on 58 patients. Patients with a poor performance status commonly underwent VATS. Meanwhile, patients with infection extending to both the anterior and posterior lower mediastinum frequently underwent thoracotomy. Although the postoperative 90-day mortality was different between the VATS and thoracotomy groups (4.8% vs 8.6%), the adjusted risk difference was almost the same, -0.0077 with 95% confidence interval of -0.0959 to 0.0805 (P = 0.8649). Moreover, we could not find any clinical and statistical differences between the 2 groups in terms of postoperative 30-day and 1-year mortality. Although patients who underwent VATS had higher postoperative complication (53.0% vs 24.1%) and reoperation (37.9% vs 15.5%) rates than those who underwent thoracotomy, the complications were not serious and most could be treated with reoperation and intensive care.

Conclusions

The outcome of DNM treatment does not depend on thoracotomy or VATS.

SUBMITTER: Tanaka Y 

PROVIDER: S-EPMC10133401 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature

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Publications

The efficacy of thoracoscopic surgery for descending necrotizing mediastinitis.

Tanaka Yugo Y   Maniwa Yoshimasa Y   Sugio Kenji K   Okamoto Tatsuro T   Nibu Ken-Ichi KI   Omori Takashi T   Endo Shunsuke S   Kuwano Hiroyuki H   Chida Masayuki M   Toh Yasushi Y   Okada Morihito M   Shiotani Akihiro A   Yoshino Ichiro I  

Interdisciplinary cardiovascular and thoracic surgery 20230401 4


<h4>Objectives</h4>Thoracotomy is a reliable approach for descending necrotizing mediastinitis (DNM), and the use of video-assisted thoracic surgery (VATS), a minimally invasive procedure, has been increasing. However, which approach is more effective for DNM treatment is controversial.<h4>Methods</h4>We analysed patients who underwent mediastinal drainage via VATS or thoracotomy, using a database with DNM from 2012 to 2016 in Japan, which was constructed by the Japanese Association for Chest Su  ...[more]

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