Functional characterization of hypothetical proteins from Monkeypox virus.

ABSTRACT:

Background

Monkeypox virus is a small, double-stranded DNA virus that causes a zoonotic disease called Monkeypox. The disease has spread from Central and West Africa to Europe and North America and created havoc in some countries all around the world. The complete genome of the Monkeypox virus Zaire-96-I-16 has been sequenced. The viral strain contains 191 protein-coding genes with 30 hypothetical proteins whose structure and function are still unknown. Hence, it is imperative to functionally and structurally annotate the hypothetical proteins to get a clear understanding of novel drug and vaccine targets. The purpose of the study was to characterize the 30 hypothetical proteins through the determination of physicochemical properties, subcellular characterization, function predicti

SUBMITTER: Gupta K 

PROVIDER: S-EPMC10133424 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature