Attributable mortality due to nosocomial sepsis in Brazilian hospitals: a case-control study.

ABSTRACT:

Background

Nosocomial sepsis is a major healthcare issue, but there are few data on estimates of its attributable mortality. We aimed to estimate attributable mortality fraction (AF) due to nosocomial sepsis.

Methods

Matched 1:1 case-control study in 37 hospitals in Brazil. Hospitalized patients in participating hospitals were included. Cases were hospital non-survivors and controls were hospital survivors, which were matched by admission type and date of discharge. Exposure was defined as occurrence of nosocomial sepsis, defined as antibiotic prescription plus presence of organ dysfunction attributed to sepsis without an alternative reason for organ failure; alternative definitions were explored. Main outcome measurement was nosocomial sepsis-attributable fractions, estimat

SUBMITTER: Zampieri FG 

PROVIDER: S-EPMC10133434 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature