Lung volume reduction surgery versus endobronchial valves: a randomised controlled trial.

ABSTRACT:

Background

Lung volume reduction surgery (LVRS) and bronchoscopic lung volume reduction (BLVR) with endobronchial valves can improve outcomes in appropriately selected patients with emphysema. However, no direct comparison data exist to inform clinical decision making in people who appear suitable for both procedures. Our aim was to investigate whether LVRS produces superior health outcomes when compared with BLVR at 12 months.

Methods

This multicentre, single-blind, parallel-group trial randomised patients from five UK hospitals, who were suitable for a targeted lung volume reduction procedure, to either LVRS or BLVR and compared outcomes at 1 year using the i-BODE score. This composite disease severity measure includes body mass index, airflow obstruction, dyspnoea and exe

SUBMITTER: Buttery SC 

PROVIDER: S-EPMC10133584 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature