Alcoholic liver disease in relation to cancer incidence and mortality: Findings from a large, matched cohort study in South Korea.

ABSTRACT:

Aim

To estimate the risk of cancer incidence and mortality among patients with alcoholic liver disease in South Korea.

Methods

A matched cohort study was conducted, including 1,042,185 men (alcoholic liver disease cases: 208,437; controls: 833,748) and 100,400 women (alcoholic liver disease cases: 20,080; controls: 80,320), matched for sex, age, smoking, alcohol consumption, and body mass index at a 1:4 ratio. The risk of cancer incidence and mortality in the alcoholic liver disease group was assessed using Cox proportional hazards regression models.

Results

Both men and women with alcoholic liver disease had an elevated risk of all-cancer and liver cancer incidence and mortality in comparison with the control group. In men, alcoholic liver disease was associated with

SUBMITTER: Tran TPT 

PROVIDER: S-EPMC10134281 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature