Dose-volume constraints for head-and-neck cancer in carbon ion radiotherapy: A literature review.

ABSTRACT:

Background

Carbon ion radiotherapy (CIRT) has been applied in cancer treatment for over 25 years. However, guidelines for dose-volume constraints have not been established yet. The aim of this review is to summarize the dose-volume constraints in CIRT for head-and-neck (HN) cancer that were determined through previous clinical studies based on the Japanese models for relative biological effectiveness (RBE).

Methods

A literature review was conducted to identify all constraints determined for HN cancer CIRT that are based on the Japanese RBE models.

Results

Dose-volume constraints are reported for 17 organs at risk (OARs), including the brainstem, ocular structures, masticatory muscles, and skin. Various treatment planning strategies are also presented for reducing the

SUBMITTER: Varnava M 

PROVIDER: S-EPMC10134371 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature