Patterns of care and outcome of CIC-rearranged sarcoma patients: A nationwide study of the French sarcoma group.

ABSTRACT:

Background

CIC-rearranged sarcomas (CIC-RS) represent the most frequent subset of "Ewing-like" undifferentiated small round cell sarcomas. These tumors tend to be more aggressive than Ewing sarcomas. Moreover, treatment strategy can differ according to teams. The primary aim of this retrospective study was to describe the characteristics, treatments, and outcome for patients with CIC-RS included in the French NETSARC+ database.

Methods

Pediatric and adult patients from 13 French centers with a diagnosis of CIC-RS were registered from October 2008 to March 2021. Patients and tumors characteristics were collected from the national network NETSARC+ database (http://netsarc.sarcomabcb.org). CIC-RS diagnosis was pathologically and molecularly confirmed with a central review by ex

SUBMITTER: Brahmi M 

PROVIDER: S-EPMC10134374 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature