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Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines.

ABSTRACT: A new triterpenoid was isolated from the roots of Jasminum sambac (L.) Ait. Its structure was elucidated by 1D and 2D NMR analysis, single crystal X-ray diffraction, and HRESIMS. This compound exhibited potent in vitro anticancer efficacy against MCF-7 cell lines with IC₅₀'s of 193.5 μM for 24 h and 154.6 μM for 48 h.

SUBMITTER: Olatunde OZ

PROVIDER: S-EPMC10134469 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature

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Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines.

Olatunde Olagoke Zacchaeus OZ Yong Jianping J Lu Canzhong C

ACS omega 20230412 16

A new triterpenoid was isolated from the roots of Jasminum sambac (L.) Ait. Its structure was elucidated by 1D and 2D NMR analysis, single crystal X-ray diffraction, and HRESIMS. This compound exhibited potent in vitro anticancer efficacy against MCF-7 cell lines with IC50's of 193.5 μM for 24 h and 154.6 μM for 48 h. ...[more]

PMID: 37125138

Dataset Information

Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines.

Publications

Isolation, Structural Elucidation of a New Triterpenoid from the Roots of <i>Jasminum sambac</i> (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines.

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