A systematic study on the use of multifunctional nanodiamonds for neuritogenesis and super-resolution imaging.

ABSTRACT:

Background

Regeneration of defective neurons in central nervous system is a highlighted issue for neurodegenerative disease treatment. Various tissue engineering approaches have focused on neuritogenesis to achieve the regeneration of damaged neuronal cells because damaged neurons often fail to achieve spontaneous restoration of neonatal neurites. Meanwhile, owing to the demand for a better diagnosis, studies of super-resolution imaging techniques in fluorescence microscopy have triggered the technological development to surpass the classical resolution dictated by the optical diffraction limit for precise observations of neuronal behaviors. Herein, the multifunctional nanodiamonds (NDs) as neuritogenesis promoters and super-resolution imaging probes were studied.

Methods

To

SUBMITTER: Kim J 

PROVIDER: S-EPMC10134586 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature