Immunomodulatory effects of modified Liu-Wei-Di-Huang-Wan Traditional Chinese medicine on allergic asthmatic mice.

ABSTRACT:

Background

Allergic asthma occurs worldwide and is particularly prevalent in westernized countries characterized by chronic airway inflammation resulting in airway hyperresponsiveness. The house dust mites (HDM) including Dermatophagoides pteronyssinus are major sources of sensitization and triggering allergic symptoms in asthmatic patients. The Der p 2 is a major allergen and the predominant source of causative respiratory disorders which induce airway inflammation and bronchial constriction in mite-allergic patients. Few studies evaluate the ameliorating effects of modified Liu-Wei-Di-Huang-Wan (modified LWDHW) on allergic asthma.

Methods

This study aimed to investigate the immunological mechanisms of modified LWDHW on the reductions of airway inflammation, signal transduc

SUBMITTER: Tsai JJ 

PROVIDER: S-EPMC10134635 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature