MALDI-TOF MS: An alternative approach for ribotyping Clostridioides difficile isolates in Brazil.

ABSTRACT: Clostridioides difficile is an important organism causing healthcare-associated infections. It has been documented that specific strains caused multiple outbreaks globally, and patients infected with those strains are more likely to develop severe C. difficile infection (CDI). With the appearance of a variant strain, BI/NAP1 ribotype 027, responsible for several outbreaks and high mortality rates worldwide, the epidemiology of the CDI changed drastically in the United States, Europe, and some Latin American countries. Although the epidemic strain 027 was not yet detected in Brazil, there are ribotypes exclusively found in the country, such as, 131, 132, 133, 135, 142 and 143, which are responsible for outbreaks in Brazilian hospitals and nursing homes. Although PCR-ribotyping is the most u

SUBMITTER: Carneiro LG 

PROVIDER: S-EPMC10134784 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature