Promising Bioactivity of Vitamin B₁-Au Nanocluster: Structure, Enhanced Antioxidant Behavior, and Serum Protein Interaction.

ABSTRACT: In the current work, we first present a simple synthesis method for the preparation of novel Vitamin-B₁-stabilized few-atomic gold nanoclusters with few atomic layers. The formed nanostructure contains ca. eight Au atoms and shows intensive blue emissions at 450 nm. The absolute quantum yield is 3%. The average lifetime is in the nanosecond range and three main components are separated and assigned to the metal-metal and ligand-metal charge transfers. Based on the structural characterization, the formed clusters contain Au in zero oxidation state, and Vitamin B₁ stabilizes the metal cores via the coordination of pyrimidine-N. The antioxidant property of the Au nanoclusters is more prominent than that of the pure Vitamin B₁, which is confirmed by two differe

SUBMITTER: Ungor D 

PROVIDER: S-EPMC10135240 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature