The Role of Genetic Polymorphisms in Differentiated Thyroid Cancer: A 2023 Update.

ABSTRACT: Thyroid cancer is the most common endocrine malignancy, with an increasing trend in the past decades. It has a variety of different histological subtypes, the most frequent one being differentiated thyroid cancer, which refers to papillary carcinoma, the most common histological type, followed by follicular carcinoma. Associations between genetic polymorphisms and thyroid cancer have been investigated over the years and are an intriguing topic for the scientific world. To date, the results of associations of single nucleotide polymorphisms, the most common genetic variations in the genome, with thyroid cancer have been inconsistent, but many promising results could potentially influence future research toward developing new targeted therapies and new prognostic biomarkers, thus consolidati

SUBMITTER: Tiuca RA 

PROVIDER: S-EPMC10135953 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature