Epileptic Tissue Localization through Skewness-Based Functional Connectivity in the High-Frequency Band of Intracranial EEG.

ABSTRACT: Functional connectivity analysis of intracranial electroencephalography (iEEG) plays an important role in understanding the mechanism of epilepsy and seizure dynamics. However, existing connectivity analysis is only suitable for low-frequency bands below 80 Hz. High-frequency oscillations (HFOs) and high-frequency activity (HFA) in the high-frequency band (80-500 Hz) are thought to be specific biomarkers in epileptic tissue localization. However, the transience in duration and variability of occurrence time and amplitudes of these events pose a challenge for conducting effective connectivity analysis. To deal with this problem, we proposed skewness-based functional connectivity (SFC) in the high-frequency band and explored its utility in epileptic tissue localization and surgical outcome e

SUBMITTER: Shen M 

PROVIDER: S-EPMC10136084 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature