Identification of Critical Genes for Ovine Horn Development Based on Transcriptome during the Embryonic Period.

ABSTRACT: Horns, also known as headgear, are a unique structure of ruminants. As ruminants are globally distributed, the study of horn formation is critical not only for increasing our understanding of natural and sexual selection but also for the breeding of polled sheep breeds to facilitate modern sheep farming. Despite this, a significant number of the underlying genetic pathways in sheep horn remain unclear. In this study, to clarify the gene expression profile of horn buds and investigate the key genes in horn bud formation, RNA-sequencing (RNA-seq) technology was utilized to investigate differential gene expression in the horn buds and adjacent forehead skin of Altay sheep fetuses. There were only 68 differentially expressed genes (DEGs) identified, consisting of 58 up-regulated genes and 10 d

SUBMITTER: Luan Y 

PROVIDER: S-EPMC10136283 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature