Dataset Information

Partial Hepatic Vein Occlusion and Venous Congestion in Liver Exploration Using a Hyperspectral Camera: A Proposal for Monitoring Intraoperative Liver Perfusion.

ABSTRACT:

Introduction

The changes occurring in the liver in cases of outflow deprivation have rarely been investigated, and no measurements of this phenomenon are available. This investigation explored outflow occlusion in a pig model using a hyperspectral camera.

Methods

Six pigs were enrolled. The right hepatic vein was clamped for 30 min. The oxygen saturation (StO₂%), deoxygenated hemoglobin level (de-Hb), near-infrared perfusion (NIR), and total hemoglobin index (THI) were investigated at different time points in four perfused lobes using a hyperspectral camera measuring light absorbance between 500 nm and 995 nm. Differences among lobes at different time points were estimated by mixed-effect linear regression.

Results

StO₂% decreased over time in the right lateral lobe (RLL, totally occluded) when compared to the left lateral (LLL, outflow preserved) and the right medial (RML, partially occluded) lobes (p < 0.05). De-Hb significantly increased after clamping in RLL when compared to RML and LLL (p < 0.05). RML was further analyzed considering the right portion (totally occluded) and the left portion of the lobe (with an autonomous draining vein). StO₂% decreased and de-Hb increased more smoothly when compared to the totally occluded RLL (p < 0.05).

Conclusions

The variations of StO₂% and deoxy-Hb could be considered good markers of venous liver congestion.

SUBMITTER: Famularo S

PROVIDER: S-EPMC10136658 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature

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Publications

Partial Hepatic Vein Occlusion and Venous Congestion in Liver Exploration Using a Hyperspectral Camera: A Proposal for Monitoring Intraoperative Liver Perfusion.

Famularo Simone S Bannone Elisa E Collins Toby T Reitano Elisa E Okamoto Nariaki N Mishima Kohei K Riva Pietro P Tsai Yu-Chieh YC Nkusi Richard R Hostettler Alexandre A Marescaux Jacques J Felli Eric E Diana Michele M

Cancers 20230421 8

<h4>Introduction</h4>The changes occurring in the liver in cases of outflow deprivation have rarely been investigated, and no measurements of this phenomenon are available. This investigation explored outflow occlusion in a pig model using a hyperspectral camera.<h4>Methods</h4>Six pigs were enrolled. The right hepatic vein was clamped for 30 min. The oxygen saturation (StO<sub>2</sub>%), deoxygenated hemoglobin level (de-Hb), near-infrared perfusion (NIR), and total hemoglobin index (THI) were ...[more]

PMID: 37190325

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Dataset Information

Partial Hepatic Vein Occlusion and Venous Congestion in Liver Exploration Using a Hyperspectral Camera: A Proposal for Monitoring Intraoperative Liver Perfusion.

Introduction

Methods

Results

Conclusions

Publications

Partial Hepatic Vein Occlusion and Venous Congestion in Liver Exploration Using a Hyperspectral Camera: A Proposal for Monitoring Intraoperative Liver Perfusion.

Similar Datasets

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