The Optimal Cutoff Value of Tumor Markers for Prognosis Prediction in Ampullary Cancer.

ABSTRACT:

Background

Carbohydrate antigen 19-9 (CA 19-9) is a representative tumor marker used for the diagnosis of pancreatic and biliary tract cancers. There are few published research results that can be applied to actual clinical practice for ampullary cancer (AC) alone. This study aimed to demonstrate the relationship between the prognosis of AC and the level of CA 19-9, and to determine the optimal thresholds.

Methods

Patients who underwent curative resection (pancreaticoduodenectomy (PD) or pylorus preserving pancreaticoduodenectomy (PPPD)) for AC at the Seoul National University Hospital between January 2000 and December 2017 were enrolled. To determine the optimal cutoff values that could clearly stratify the survival outcome, the conditional inference tree (C-tree) method wa

SUBMITTER: Lee S 

PROVIDER: S-EPMC10136701 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature