Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders.

ABSTRACT: Imaging genetics provides an opportunity to discern associations between genetic variants and brain imaging phenotypes. Historically, the field has focused on adults and adolescents; very few imaging genetics studies have focused on brain development in infancy and early childhood (from birth to age 6 years). This is an important knowledge gap because developmental changes in the brain during the prenatal and early postnatal period are regulated by dynamic gene expression patterns that likely play an important role in establishing an individual's risk for later psychiatric illness and neurodevelopmental disabilities. In this review, we summarize findings from imaging genetics studies spanning from early infancy to early childhood, with a focus on studies examining genetic risk for neuropsy

SUBMITTER: Alex AM 

PROVIDER: S-EPMC10136952 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature