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Epigenetic Modifications in Prostate Cancer Metastasis and Microenvironment.


ABSTRACT: The gradual evolution of prostate tissue from benign tumor to malignant lesion or distant metastasis is driven by intracellular epigenetic changes and the tumor microenvironment remodeling. With the continuous study of epigenetic modifications, these tumor-driving forces are being discovered and are providing new treatments for cancer. Here we introduce the classification of epigenetic modification and highlight the role of epigenetic modification in tumor remodeling and communication of the tumor microenvironment.

SUBMITTER: Zhang S 

PROVIDER: S-EPMC10137161 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature

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Epigenetic Modifications in Prostate Cancer Metastasis and Microenvironment.

Zhang Shouyi S   Shen Tao T   Zeng Yu Y  

Cancers 20230411 8


The gradual evolution of prostate tissue from benign tumor to malignant lesion or distant metastasis is driven by intracellular epigenetic changes and the tumor microenvironment remodeling. With the continuous study of epigenetic modifications, these tumor-driving forces are being discovered and are providing new treatments for cancer. Here we introduce the classification of epigenetic modification and highlight the role of epigenetic modification in tumor remodeling and communication of the tum  ...[more]

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