Impact of Potentially Inappropriate Medications on Kidney Function in Chronic Kidney Disease: Retrospective Cohort Study.

ABSTRACT:

Introduction

Chronic kidney disease (CKD) represents a major public health burden. Potential inappropriate medications (PIMs) are common in patients with CKD. However, its impact on kidney outcomes has not been adequately elucidated for middle-aged patients. This study aimed to clarify the prescription status of PIMs for middle-aged patients with CKD and its effect on kidney function decline.

Methods

Using an administrative claims database in Japan, a retrospective cohort study was conducted among Japanese patients with CKD (aged 20-74) who underwent annual health check-ups at least three times between April 2008 and December 2020. PIM exposure was defined as medications to be avoided in older adults as defined by the 2019 American Geriatrics Society Beers Criteria. The asso

SUBMITTER: Kimura H 

PROVIDER: S-EPMC10137306 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature