Development of an Algorithm to Differentiate Uterine Sarcoma from Fibroids Using MRI and LDH Levels.

ABSTRACT:

Background

This study aimed to establish an evaluation method for detecting uterine sarcoma with 100% sensitivity using MRI and serum LDH levels.

Methods

One evaluator reviewed the MRI images and LDH values of a total of 1801 cases, including 36 cases of uterine sarcoma and 1765 cases of uterine fibroids. The reproducibility of the algorithm was also examined by four evaluators with different imaging experience and abilities, using a test set of 61 cases, including 14 cases of uterine sarcoma.

Results

From the MRI images and LDH values of 1801 cases of uterine sarcoma and uterine fibroids, we found that all sarcomas were included in the group with a high T2WI and either a high T1WI, an unclear margin, or high LDH values. In addition, when cases with DWI were examined,

SUBMITTER: Suzuki A 

PROVIDER: S-EPMC10137865 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature