Recent Advances in Hydrogel-Based Phototherapy for Tumor Treatment.

ABSTRACT: Phototherapeutic agent-based phototherapies activated by light have proven to be safe modalities for the treatment of various malignant tumor indications. The two main modalities of phototherapies include photothermal therapy, which causes localized thermal damage to target lesions, and photodynamic therapy, which causes localized chemical damage by generated reactive oxygen species (ROS). Conventional phototherapies suffer a major shortcoming in their clinical application due to their phototoxicity, which primarily arises from the uncontrolled distribution of phototherapeutic agents in vivo. For successful antitumor phototherapy, it is essential to ensure the generation of heat or ROS specifically occurs at the tumor site. To minimize the reverse side effects of phototherapy while improvi

SUBMITTER: Gan S 

PROVIDER: S-EPMC10137920 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature