Association between the PPARGC1A Gly482Ser polymorphism and muscle fitness in Chinese schoolchildren.

ABSTRACT:

Objectives

Muscle health is essential for children's physical development and future health. PPARGC1A gene encode the peroxisome proliferator-activated receptor coactivator 1α which coactivates transcription factors that control mediating skeletal muscle fiber type conversion and skeletal muscle fiber formation. The PPARGC1A rs8192678 Gly/Ser (Gly482Ser) polymorphism was associated with the regulation of skeletal muscle fibre type. This paper aims to explore the association between the PPARGC1A rs8192678 (Gly482Ser) polymorphism and muscle fitness in Chinese schoolchildren.

Methods

We detected the distribution of the PPARGC1A rs8192678 (Gly482Ser) polymorphism by DNA typing of saliva samples from untrained Southern Chinese Han children aged 7-12 years. Considering that muscl

SUBMITTER: Wei Q 

PROVIDER: S-EPMC10138255 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature