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Cardiovascular Complications in Patients with Prostate Cancer: Potential Molecular Connections.


ABSTRACT: Cardiovascular diseases (CVDs) and complications are often seen in patients with prostate cancer (PCa) and affect their clinical management. Despite acceptable safety profiles and patient compliance, androgen deprivation therapy (ADT), the mainstay of PCa treatment and chemotherapy, has increased cardiovascular risks and metabolic syndromes in patients. A growing body of evidence also suggests that patients with pre-existing cardiovascular conditions show an increased incidence of PCa and present with fatal forms of the disease. Therefore, it is possible that a molecular link exists between the two diseases, which has not yet been unraveled. This article provides insight into the connection between PCa and CVDs. In this context, we present our findings linking PCa progression with patients

SUBMITTER: Kakkat S 

PROVIDER: S-EPMC10138415 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature