Peripapillary choroidal microvasculature dropout is associated with poor prognosis in optic neuritis.

ABSTRACT:

Purpose

To identify peripapillary choroidal microvasculature dropout (MvD) in eyes with optic neuritis and its association with longitudinal changes in retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIP) thicknesses following diagnosis.

Methods

A total of 48 eyes with optic neuritis was evaluated to identify the presence of peripapillary choroidal MvD, defined as a focal capillary loss with no visible microvascular network in choroidal layer, using optical coherence tomography (OCT) angiography (OCTA). Patients were divided based on the presence of MvD. OCT and standard automated perimetry (SAP) conducted at 1, 3 and 6 months follow-up were analyzed.

Results

MvD was identified in 20 of 48 eyes (41.7%) with optic neuritis. MvD was most commo

SUBMITTER: Lee JS 

PROVIDER: S-EPMC10138827 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature