Genomic analysis of two phlebotomine sand fly vectors of Leishmania from the New and Old World.

ABSTRACT: Phlebotomine sand flies are of global significance as important vectors of human disease, transmitting bacterial, viral, and protozoan pathogens, including the kinetoplastid parasites of the genus Leishmania, the causative agents of devastating diseases collectively termed leishmaniasis. More than 40 pathogenic Leishmania species are transmitted to humans by approximately 35 sand fly species in 98 countries with hundreds of millions of people at risk around the world. No approved efficacious vaccine exists for leishmaniasis and available therapeutic drugs are either toxic and/or expensive, or the parasites are becoming resistant to the more recently developed drugs. Therefore, sand fly and/or reservoir control are currently the most effective strategies to break transmission. To better und

SUBMITTER: Labbe F 

PROVIDER: S-EPMC10138862 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature