Retinitis Pigmentosa: Current Clinical Management and Emerging Therapies.

ABSTRACT: Retinitis pigmentosa (RP) comprises a group of inherited retinal dystrophies characterized by the degeneration of rod photoreceptors, followed by the degeneration of cone photoreceptors. As a result of photoreceptor degeneration, affected individuals experience gradual loss of visual function, with primary symptoms of progressive nyctalopia, constricted visual fields and, ultimately, central vision loss. The onset, severity and clinical course of RP shows great variability and unpredictability, with most patients already experiencing some degree of visual disability in childhood. While RP is currently untreatable for the majority of patients, significant efforts have been made in the development of genetic therapies, which offer new hope for treatment for patients affected by inherited ret

SUBMITTER: Nguyen XT 

PROVIDER: S-EPMC10139437 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature