A novel anterior nasal swab to detect respiratory viruses: a prospective study of diagnostic accuracy.

ABSTRACT: Detection of respiratory viruses requires testing of the upper respiratory tract to obtain specimens for analysis. However, nasal and throat swabs can cause discomfort and procedural anxiety in children. Respiratory sampling methods which are accurate and less invasive are needed. We aim to determine the positive and negative percentage agreement of a novel anterior nasal swab (ANS) compared with the combined throat and anterior nasal swab (CTN), the reference standard, for detection of respiratory viruses. Children 5 - 18 years of age presenting to a tertiary paediatric hospital with respiratory symptoms were tested with both swabs in randomised order. Respiratory samples were tested on a multiplex RT-PCR panel. Viral detections, RT-PCR cycle-threshold values and child/parent/clinician ex

SUBMITTER: Tosif S 

PROVIDER: S-EPMC10139914 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature